Publications

• Y. Berlin, A. Burin, J. Friedrich and J. Köhler
  Spectroscopy of Proteins at low temperature. Part I: Experiments with molecular ensembles
  Phys. of Life Rev., 3, 262-292 (2006)
• Mark M. Somoza, Vladimir V. Ponkratov and Josef Friedrich
  Investigation of spectral diffusion in ribonuclease by photolabeling of intrinsic aromatic amino acids
  J. Chem. Phys., 125, 194713 (2006)
• Mark M. Somoza and Josef Friedrich
  The physics of rotational tunneling: hole-burning spectroscopy of methyl groups
  Low Temp. Phys., 32, (2006)
• V.V. Ponkratov, J. Friedrich and J.M. Vanderkooi
  Hole burning experiments with proteins: Relaxations, fluctuations and glass-like features
  J. Non-Crystalline Solids, 352, 4379-4386 (2006)
• Ronald Gebhardt, Wolfgang Doster, Josef Friedrich, U. Kulozik
  Size distribution of pressure-decomposed casein micelles studied by dynamic light scattering and AFM
  Eur. Biophys. J., 35, 503-509 (2006)
• M. M. Somoza, J. Friedrich
  Thermal-cycling-induced spectral diffusion and thermal barriers in anisole-doped cyclohexane, an unusual multiphase host-guest system
  J. Phys. Chem. B, 110, 18828 (2006)
• Christoph Schnell, Christina Scharnagl, Josef Friedrich
  Hole burning spectroscopy of ribonuclease A
  Phys. Chem. Chem. Phys. 8, 1315-1320 (2006)
• M.M. Somoza, J. Friedrich and H.P. Trommsdorff
  Light scattering and spectral inversion in a matrix-isolated molecule
  Chem. Phys. Lett. 420, 4-6, 534-537 (2006)

• Christoph Hecht, Peter Hermann, Josef Friedrich, Cheng-Chung Chang, Ta-Chau Chang
  Thionin in a cyclodextrin nanocavity: Measuring local compressibilities by pressure tuning hole burning spectroscopy
  Chem. Phys. Lett. 413, 335-341, (2005)
• C. Schnell, M. Reif, C. Scharnagl and J. Friedrich
  Local compressibilities in insulin as determined from pressure tuning hole burning experiments and MD simulations
  Phys. Chem. Chem. Phys., 7, 2217-2224 (2005)
• C. Scharnagl, M. Reif and J. Friedrich
  Local compressibilities of proteins: Comparison of optical experiments and simulations for horse heart cytochrome c
  Biophys. J., 89, 64-75 (2005)
• C. Scharnagl, M. Reif and J. Friedrich
  Stability of proteins: Temperature, pressure and the role of the solvent
  Biochim. Biophys. Acta, 1749, 187-213 (2005)
• Ta-Chau Chang, Yih-Peh Yang, Kai-Hsiang Huang, Cheng-Chung Chang and Christoph Hecht
  Investigation of Thionin-DNA Interaction by Satellite Hole Spectroscopy
  Optics and Spectroscopy, 98, (5), 655-660, (2005)

• Harald Lesch, Christoph Hecht, Josef Friedrich
  Protein phase diagrams: The physics behind their elliptic shape
  J. Chem. Phys., 121, 12671 (2004)
• P. Müller-Buschbaum, N. Hermsdorf, S. V. Roth, J. Wiedersich, S. Cunis, R. Gehrke
  Comparative analysis of nanostructured diblock copolymer films
  Spectrochimica Acta Part B, 59, 1789 (2004)
• Levente Herenyi, Krisztian Szigeti, Judit Fidy, Tamas Temesvari, Jörg Schlichter, Josef Friedrich
  Aging dynamics in globular proteins: summary and analysis of experimental results and simulation by a modified trap model
  Eur. Biophys. J, 33, 68 (2004)
• Christoph Hecht, Markus Stübner, Josef Friedrich, and Ta-Chau Chang
  Investigation of Probe Solvent Interactions: Color Effects in Optical Line Widths
  Chem. Phys. Lett., 395, 21 (2004)
• W. Doster, J. Friedrich
  Pressure-Temperature Phase Diagrams of Proteins
  Protein Folding Handbook. Part I, ed. J. Buchner and T. Kiefhaber, Wiley-VCH Verlag, Weinheim (2004)
• V. V. Ponkratov, J. Friedrich, J. Vanderkooi, A. L. Burin, Y. A. Berlin
  Physics of Proteins at Low Temperature
  J. Low Temp. Phys., 137 (3/4) (2004)
• Josef Friedrich
  Hole burning
  Encyclopedia of Nonlinear Science, ed. Alwyn Scott. New York and London: Routledge (2004)
• Christoph Hecht, Josef Friedrich, and Ta-Chau Chang
  Interactions of Thionin with DNA Strands: Intercalation versus External Stacking
  J. Phys. Chem. B, 108, 10241 (2004)
• Vladimir V. Ponkratov, Josef Friedrich, Dejan Markovic, Hugo Scheer, Jane M. Vanderkooi
  Spectral Diffusion Experiment with a Denatured Protein
  J. Phys. Chem. B, 108, 1109 (2004)
• H. Lesch, J. Schlichter, J. Friedrich, J. M. Vanderkooi
  Molecular Probes: What is the Range of Their Interaction with the Environment?
  Biophysical Journal, 86, 467 (2004)
• Christina Scharnagl, Robert A. Raupp-Kossmann
  Solution pK_a Values of the Green Fluorescent Protein Chromophore from Hybrid Quantum-Classical Calculations
  J. Phys. Chem. B, 108, 477-489 (2004)

• R. Gebhardt, W. Doster, J. Friedrich, W. Petry, A. Schulte
  Pressure-Induced Critical Association of Myoglobin
  Ed. R. Winter, Springer-Verlag
  Advances in High Pressure Bioscience and Biotechnology II, p. 33 (2003)
• J. Schlichter, V. V. Ponkratov, J. Friedrich
  Structural fluctuations and aging processes in deeply frozen proteins
  Low Temp. Phys., 29, 795, (2003)
• N. V. Surovtsev, S. V. Adichtchev, J. Wiedersich, V. N. Novikov, E. A. Rössler
  Fast relaxation in the structural glass and glassy crystal of ethanol and cyano cyclohexane: a quasielastic light scattering study
  J. Chem. Phys., 119, 12399-12408 (2003)
• M. Stübner, P. Schellenberg
  Low-Temperature Photochemistry and Photodynamics of the Chromophore of Green Fluorescent Protein (GFP)
  J. Phys. Chem. A, 107, 1246-1252 (2003)
• Y.-P. Yang, T.-C. Chang, M. Stübner, J. Friedrich
  Influence of Pressure on the Spectral Properties of Dye-DNA Supermolecules
  J. Phys. Chem. B, 107, 1458-1465 (2003)

• M. Stübner, Ch. Hecht, E. Schneider, J. Friedrich
  Hole Burning Stark-Effect Studies on Aromatic Aminoacids: II. A comparative investigation of tyrosine and the BPTI-protein
  Phys. Chem. Chem. Phys., 4, 6080-6085 (2002)
• M. Stübner, Ch. Hecht, J. Friedrich
  Labeling proteins via hole burning of their aromatic amino acids: Pressure tuning spectroscopy of BPTI
  Biophys. J., 83, 3553-3557 (2002)
• M. Pinsker, J. Friedrich
  Methyl group rotational tunneling splittings and spin conversion dynamics: p-chlortoluene in cyclohexane
  J. Chem. Phys., 117, 4639-4642 (2002)
• S. V. Adichtchev, N. Bagdassarov, St. Benkhof, Th. Blochowicz, V. N. Novikov, E. Rössler, N. V. Surovtsev, Ch. Tschirwitz, J. Wiedersich
  Evolution of the dynamic susceptibility of paradigmatic glass formers below the critical temperature T_c as revealed by light scattering
  J. Non-Cryst. Solids, 307-310, 24-31 (2002)
• V.V. Ponkratov, J. Friedrich and J. M. Vanderkooi
  Solvent effects on conformational dynamics of proteins: Cytochrome c in a dried trehalose film
  J. Chem. Phys, 117(9), 4594-4601 (2002)
• M. Stübner, J. Friedrich, Yih-Pey Yang and Ta-Chau Chang
  Using external field effects for elucidating specific features in dye-DNA-interactions
  J. Lum., 98, 153-161 (2002)
• J. Schlichter, J. Friedrich, L. Herenyi, J. Fidy
  Deuteration Effects on the Conformational Dynamics of Proteins in a Trehalose Glass
  J. Phys. Chem. B, 106 (13), 3510 -3514, (2002)
• A.L. Burin, Yu.A. Berlin, A.Z. Patashinski, M.A. Ratner, J. Friedrich
  Fluctuations of conformational states in biological molecules: theory for anomalous spectral diffusion dynamics
  Physica B: Phys. of Condensed Matter, 316-317C, 321-323 (2002)
• V.N. Novikov, N.V. Surovtsev, J. Wiedersich, S. Adichtchev, S. Kojima, E. Rössler
  On the origin of quasi-elastic light scattering in glasses
  Europhys. Lett., 57 (6), pp. 838-844 (2002)
• H. Lesch, H. Stadlbauer, J. Friedrich, J. M. Vanderkooi
  Stability Diagram and Unfolding of a Modified Cytochrome c: What Happens in the Transformation Regime?
  Biophys. J. 82, 1644-1653 (2002)
• S. V. Adichtchev, St. Benkhof, Th. Blochowicz, V. N. Novikov, E. Rössler, Ch. Tschirwitz, and J. Wiedersich
  Anomaly of the non-ergodicity parameter and crossover to white noise in the fast relaxation spectrum of a simple glass former
  Phys. Rev. Lett. 88, 055703 (2002)
• W. Doster, M. Diehl, H. Schober, W. Petry, J. Wiedersich
  Effect of pressure and pressure-denaturation on fast molecular motions of solvated myoglobin
  Trends in High Pressure Bioscience and Biotechnology, edited by R. Hayashi, Elsevier, p. 107 (2002)

• M. Stübner, E. Schneider and J. Friedrich
  Hole burning Stark-effect studies on aromatic aminoacids: I. Phenylalanine in a glycerol-water glass
  Phys. Chem. Chem. Phys., 3,5369-5372 (2001)
• J. Schlichter and J. Friedrich
  Glasses and proteins: Similarities and differences in their spectral diffusion dynamics
  J. Chem. Phys., 114, 8718-8721 (2001)
• J. Schlichter and J. Friedrich,  M. Parbel and H. Scheer
  New concepts in spectral diffusion physics of proteins
  Phot. Sci. News 6, 100-110 (2001)
• J. Schlichter, J. Friedrich, L. Herenyi and J. Fidy,
  Trehalose effect on low temperature protein dynamics: Fluctuation and relaxation phenomena
  Biophys. J., 80, 2011-2017 (2001)
• J. Schlichter, J. Friedrich, M. Parbel and H. Scheer,
  Influence of isotopic substitution on the conformational dynamics of frozen proteins
  J. Chem. Phys. 114, 9638-9644 (2001)
• M. Pinsker, J. Friedrich
  Methyl group rotation of p-chlorotoluene in cyclohexane: a nuclear spin conversion study via UV-hole burning
  Chem. Phys. Lett. 341, 545 (2001)

• E.S. Manas, W.W. Wright, K.A. Sharp, J. Friedrich, J.M. Vanderkooi
  The Influence of protein environment on the low temperature electronic spectroscopy of Zn-substituted cytochrome c
  J. Phys. Chem. B, 104, 6932 (2000)
• J. Schlichter, K.-D. Fritsch, J. Friedrich
  Dynamics of frozen proteins as investigated by optical hole burning experiments
  J. Mol. Liq., 86, 127 (2000)
• J. Schlichter, J. Friedrich, L. Herenyi, J. Fidy
  Protein dynamics at low temperatures
  J. Chem. Phys., 112, 3045 (2000)
  full article HTML or PDF

• M. Laberge, M. Köhler, J.M. Vanderkooi, J. Friedrich
  Sampling field heterogeneity at the heme of c-type cytochromes by spectral hole burning spectroscopy and electrostatic calculations
  Biophys. J. 77, 3293 (1999)
  Abstract
• J. Friedrich
  Hole burning spectroscopy
  in "Encyclopedia of spectroscopy and spectrometry",
  ed. by J. C. Lindon, G. E. Tranter, J. L. Holmes,
  Academic Press, 826 (1999)
• J.L. Skinner, J. Friedrich, J. Schlichter
  Spectral diffusion in proteins: A simple phenomenological model
  J. Phys. Chem. A 103, 2310 (1999)
• J. Schlichter, K.-D. Fritsch, J. Friedrich, J.M. Vanderkooi
  Conformational dynamics of a low temperature protein: Free base cytochrome-c
  J. Chem. Phys., 110, 3229 (1999)
  full article HTMLor PDF

• H. Pschierer, H. Wendt, J. Friedrich
  Photophysics of J-aggregates
  in "TOPOMAK: Miskroskopische Wechselwirkungen und Makroskopische Funktion"
  ed. by H. Hoffmann, M. Schwoerer, T. Vogtmann
  VCH-Verlag, 285 (1998)
• A. Suisalu, V. Zazubovich, J. Kikas, J. Friebel, J. Friedrich
  Low-temperature dynamics of incommensurate biphenyl as probed by spectral hole burning
  Europhys. Lett., 44, 613 (1998)
  full article HTML or PDF
• M. Köhler, J. Friedrich, J. Fidy
  Proteins in electric fields and pressure fields: basic aspects
  Biochem. Biophys. Acta - Protein Structure And Molecular Enzymology, 1386, 255 (1998)
  Abstract
• K. Fritsch, A. Eicker, J. Friedrich, B.M. Kharlamov, J.M. Vanderkooi
  Spectral diffusion in proteins
  Europhys. Lett., 41, 339 (1998)
  full article HTML or PDF
• J. Friebel, J. Friedrich, A. Suisalu, J. Kikas, An. Kuznetsov, A. Laisaar, K. Leiger
  Pressure-induced dynamics in solid n-alkanes as probed by optical spectroscopy
  J. Chem. Phys. 108, 1830 (1998)
  Abstract HTML or full article PDF

• M. Köhler, J. Friedrich, M. Laberge, J.M. Vanderkooi
  Influence of the pH on the pocket field of cytochrome c type proteins
  Chem. Phys., 224, 327 (1997)
• D. Thorn Leeson, D.A. Wiersma, K. Fritsch, J. Friedrich
  The energy landscape of myoglobin: An optical study
  J. Phys. Chem. B, 101, 6331 (1997)
• M. Köhler, J. Friedrich, E. Balog, J. Fidy
  Symmetry breaking by the heme pocket in horseradish peroxidase as revealed by Stark spectroscopy
  Chem. Phys. Lett., 277, 417 (1997)
• E. Balog, K. Kis-Petik, J. Fidy, M. Köhler, J. Friedrich
  Interpretation of multiple Q (0,0) bands in the absorption spectrum of Mg-mesoporphyrin embedded in horseradish peroxidase
  Biophys. J., 73, 397 (1997)
• K. Fritsch, J. Friedrich
  Spectral diffusion experiments on a myoglobin-like protein: Statistical and individual features of its energy landscape (Spectral diffusion in proteins)
  Physica D, 107, 218 (1997)

• M. Pinsker, J. Friedrich
  Hole burning spectroscopy and quantum phenomena in methyl groups
  Mol. Cryst. Liqu. Cryst., 291, 97 (1996)
• M. Johnson, K. Orth, J. Friedrich, H.P. Trommsdorff
  Rotational tunneling of partially deuterated methyl groups: Optical studies of dimethyl-s-tetrazine in different crystalline matrices
  J. Chem. Phys., 105, 9762 (1996)
  Abstract HTML or full article PDF
• K. Fritsch, J. Friedrich, F. Parak, J.L. Skinner
  Spectral diffusion and the energy landscape of a protein
  Proc. Natl. Acad. Sci. USA 93, 15141 (1996)
  full article HTML or PDF
• K. Fritsch, J. Friedrich, B.M. Kharlamov
  Nonequilibrium phenomena in spectral diffusion physics of organic glasses
  J. Chem. Phys. 105, 1798 (1996)
  Abstract HTML or full article PDF
• H. Wendt, J. Friedrich
  Hole burning Stark-spectroscopy of J-aggregates
  Chem. Phys. 210, 101 (1996)
• M. Köhler, J. Gafert, J. Friedrich, J.M. Vanderkooi, M. Laberge
  Stark effect experiments in cytochrome c-type proteins: Structural hierarchies
  Biophys. J. 71, 77 (1996)
  Abstract
• V. Gebhardt, K. Orth, J. Friedrich
  Optical spectroscopy and ground state dynamics of methyl groups
  J. Chem. Phys., 104, 942 (1996)
• M. Köhler, J. Gafert, J. Friedrich, H. Falk, J. Meyer
  Hole burning spectroscopy of proteins in external fields: Human serum albumin complexed with the hypericinate ion
  J. Phys. Chem., 100, 8567 (1996)

• H. Pschierer, J. Friedrich
  Pressure broadening and motional narrowing in excitonic states of J-aggregates
  Phys. Stat. Sol. (b) 189, 43 (1995)
• J. Gafert, J. Friedrich
  Looking into frozen proteins with hole burning
  J. Luminescence 64, 45 (1995)
• L. Herenyi, J. Fidy, J. Gafert, J. Friedrich
  Energy landscape of the tautomer states of mesoporphyrin embedded in horseradish peroxidase
  Biophys. J., 69, 577 (1995)
• J. Gafert, J. Friedrich, J.M. Vanderkooi, J. Fidy
  Structural changes and internal fields in proteins: A hole-burning Stark effect study of horseradish peroxidase
  J. Phys. Chem., 99, 5223 (1995)
• J. Gafert, H. Pschierer, J. Friedrich
  Proteins and glasses: A relaxation study in the millikelvin range
  Phys. Rev. Lett., 74, 3704 (1995)
  Abstract HTML or full article PDF
• J. Gafert, J. Friedrich, F. Parak
  Stark-effect experiments on photochemical holes in chromoproteins: protoporphyrin IX substituted myoglobin
  Proc. Natl. Acad. Sci. USA 92, 2116 (1995)
• J. Gafert, C. Ober, K. Orth, J. Friedrich
  Thermal broadening of an optical transition in a chromoprotein between 50 mK and 15 K
  J. Phys. Chem. 99, 14561 (1995)
• J. Friedrich
  Optische Spektroskopie an Biopolymeren
  in "Spektroskopie amorpher und kristalliner Festkörper"
  ed. by D. Haarer, W. Spiess
  Steinkopff-Verlag, Darmstadt, 219 (1995)
• J. Friedrich
  Hole burning spectroscopy and physics of proteins
  in "Methods of Enzymology - Biochemical Spectroscopy"
  ed. by K. Sauer
  Academic Press, San Diego, 246, 226 (1995)

• H. Pschierer, P. Schellenberg, J. Friedrich
  Pressure phenomena in spectral hole burning
  Mol. Cryst. Liqu. Cryst. 253, 113 (1994)
• K. Orth, F. Rohlfing, J. Friedrich
  Rotational tunneling dynamics of methyl groups in n-alkane host lattices: An optical investigation of the internal and external isotope effect
  Z. Phys. B 95, 493 (1994)
• P. Schellenberg, J. Friedrich, J. Kikas
  Thermal recovery and spectral diffusion of photochemical holes in polymorphic systems
  J. Chem. Phys., 101, 9262 (1994)
• J. Gafert, J. Friedrich, J.M. Vanderkooi, J. Fidy
  Correlation between protein conformation and prosthetic group configuration as tested by pH-effects: A hole-burning study of mesoporphyrin-IX-substituted horseradish peroxidase
  J. Phys. Chem. 98, 2210 (1994)
• P. Schellenberg, J. Friedrich, J. Kikas
  Spectral hole burning in polymorphic systems: Single site pressure phenomena and glassy behavior
  J. Chem. Phys. 100, 5501 (1994)
• J. Friedrich, J. Gafert, J. Zollfrank, J. Vanderkooi, J. Fidy
  Spectral hole burning and selection of conformational substates in chromoproteins
  Proc. Natl. Acad. Sci. USA, 91, 1029 (1994)
• P. Schellenberg, J. Friedrich
  Optical spectroscopy and disorder phenomena in polymers, proteins and glasses
  in "Disorder Effects on Relaxational Processes"
  ed. by A. Blumen, R. Richert
  Springer Verlag, Berlin, Heidelberg, 407 (1994)

• J. Gafert, J. Friedrich, F. Parak, J. Fidy
  Hole burning and pressure phenomena in chromoproteins
  J. Luminescence 56, 157 (1993)
• P. Schellenberg, J. Friedrich
  A pressure tuning hole burning study of resorufin in protic solvents
  J. Luminescence 56, 143 (1993)
• K. Orth, P. Schellenberg, J. Friedrich, W. Häusler
  Symmetry species conversion in rotational tunnel systems observed by hole burning: High resolution spectroscopy of dimethyl-s-tetrazine in n-octane
  J. Luminescence 56, 99 (1993)
• J. Gafert, J. Friedrich, F. Parak
  A comparative pressure tuning hole burning study of protoporphyrin-IX in myoglobin and in a glassy host
  J. Chem. Phys.,99, 2478 (1993)
• G. Kaiser, H. Pierron, J. Friedrich
  Structural disorder and spin-lattice relaxation
  J. Phys. Chem. 99, 605 (1993)
• K. Orth, P. Schellenberg, J. Friedrich
  Spin-conversion relaxation in dimethyl-s-tetrazine doped n-Octane: Deuteration and symmetry breaking
  J. Chem. Phys., 99, 1 (1993)
• H. Pschierer, J. Friedrich, H. Falk, W. Schmitzberger
  Molecular interaction and correlation phenomena between pressure shift and solvent shift: A spectral hole burning study
  J. Phys. Chem. 97, 6902 (1993)
• J. Kikas, P. Schellenberg, J. Friedrich
  Temperature broadening of impurity transitions in the crystalline and glassy phase of benzophenone
  Chem. Phys. Lett. 207, 143 (1993)